母猪杀婴行为的全基因组关联分析

doi:10.11843/j.issn.0366-6964.2016.02.005

Abstract

Abstract:

Maternal infanticide behavior in 288 sows from a White Duroc × Erhualian F₂ resource population was measured.The aim of the study was to identify the QTL affecting maternal infanticide behavior.According to pedigree information and genotyped samples with 60K chip，we speculated the 60K genotypes of the 288 tested individuals.Furthermore，a genome-wide association study was carried out to identify the significant genomic loci associated with maternal infanticide behavior using GenABEL packages in R software.We detected a total of 50 significant SNPs associated with maternal infanticide behavior on SSC2 and SSC8.Totally 21 SNPs on SSC8：35.05-47.54 Mb reached the genome-wide significant level.Only 1 SNP on SSC2：89.5 Mb reached the suggestive significance.The candidate genes around significant SNPs were searched based on its functional annotations.A total of 12 genes were found to be the most important candidate genes for maternal infanticide behavior.This study provided a foundation for identification of major gene or causative mutation influencing the maternal infanticide behavior.

CLC Number:

S828
S813.3

YANG Hui，FANG Shao-ming，HUANG Xiao-chang，CHEN Cong-ying，ZHANG Zhi-yan. Genome-Wide Association Study on Maternal Infanticide Behavior in Pigs[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(2): 241-248.

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Genome-Wide Association Study on Maternal Infanticide Behavior in Pigs

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